Is it impossible to stay awake? Hidradenitis suppurativa is a chronic inflammatory disease that causes small, painful bumps on many parts of the body, including the underarms, groin, buttocks, upper thighs, and breasts. The thick plate-like outer layer of skin eventually splits and peels at birth, leaving the vulnerable inner layers of theskinexposed. Laser therapy has also been explored as a viable option for the treatment of the disease. Seborrhea or seborrheic dermatitis is a skin disorder in which the sebaceous glands produce an excessive amount of sebum causing scaly, flaky, itchy, . Top Symptoms: being severely ill, shortness of breath at rest, wheezing, irritability, cough with dry or watery sputum, Symptoms that always occur with severe asthma attack: shortness of breath at rest, being severely ill. Bacterial pneumonia is an infection of the lungs caused by one of several different bacteria, often Streptococcus pneumoniae. Treatment options for the disease are typically topical steroids or hydroxychloroquine. "Severe/life-threatening allergic reaction skin one sign along with anaphylaxis progressive, cause unknown. The main risk factor is being born to one or both parents who have the gene. Other conditions that have been linked to IGD include: IGD has also been associated with some forms of cancer including leukemia, lymphoma, breast cancer, hyposquamous cell carcinoma, and endometrial neoplasia. Top Symptoms: cough, fever, shortness of breath, cough with dry or watery sputum, wheezing, Symptoms that always occur with foreign body aspiration: swallowing of something potentially harmful. Rachakonda TD, Schupp CW, Armstrong AW. You can prevent argyria by limiting your use of medications that contain silver and avoiding dietary supplements that contain silver. By Angelica Bottaro Melanin gives color to the skin, hair, and iris of the eyes. If youve been diagnosed with Raynauds syndrome, your doctor may advise you to dress warmly and limit your time in cold environments. Free, private and secure to get you the best way to well. This condition is called cyanosis. For example, bruises and varicose veins can appear blue in color. Oxygen-rich blood is deep red and causes your skins normal color. Homemade concoctions with this metal for treating diseases may cause . Carriers may have bluish lips and fingernails at birth, which usually lighten. Harlequin ichthyosis is a genetic disorder characterized by the thickening of the skin over most of the body at birth. Needing or ready for sleep. It can turn your skin, eyes, internal organs, nails, and gums a blue-gray color, especially in areas of your body exposed to sunlight. The affected areas typically heal without scarring. The biggest risk factor is being born to both parents with mutations in the specific gene that causes the disorder., There is no cure for acral peeling skin syndrome. Poor circulation or inadequate oxygen levels in your blood stream can also cause your skin to turn bluish. Morgellons disease: Analysis of a population with clinically confirmed microscopic subcutaneous fibers of unknown etiology. Fish scale disease can be found on any part of the body, and symptoms are less severe in a warm, humid climate. Symptoms often appear after about two months of birth and usually before the age of 5. Occasionally, peeling may also occur on the arms and legs. Over time, this condition will become life-threatening. In "blue person disease," excess oxygen-poor hemoglobin causes a dark blue complexion. What does Cyanosed mean? Healthline Media does not provide medical advice, diagnosis, or treatment. Questions may relate to diseases, illnesses, or conditions you may have or that may run in your family. Stack AM. Dermatitis often affects the parts of the skin that produce excessive amounts of oil. These include: Most causes of cyanosis are serious and a symptom of your body not getting enough oxygen. NY 10036. Many health disorders that involve the heart, lungs, blood or circulation will also cause cyanosis. Bronchiectasis is destruction and widening of the large airways. Its also more noticeable on light colored skin. Both unknowingly carried the recessive gene for the disorder. In serious cases, movement of the chest can be limited, which can lead to issues with breathing and respiratory failure. Laser therapy may also help treat argyria. Am J Case Rep. 2014;15:94-6. doi:10.12659/AJCR.890074, Wertenteil S, Garg A, Strunk A, Alloo A. The condition affects one in every 500,000 babies born every year in the United States. Treatment involves treating or eliminating the cause. That change in your skin color is permanent. When tiny blood vessels are injured, blood collects beneath the skin, causing the blue color. It has also been found in people on specific medications., Since there is no cure for fish scale disease, treatment options are designed to help cope with and manage the disease. Treatments include:. Updated May 21, 2017. Our website services, content, and products are for informational purposes only. With bacterial pneumonia, the treatment is antibiotics. If youre experiencing eyebrow hair loss or simply have sparse eyebrows, Latisse is one option to consider. Pemphigus: Signs and Symptoms. They guide and direct sebum to the surface of the skin. 2012;7(1):e29908. 2016;356(2):267-75. doi:10.1124/jpet.115.228130. Ahmed ZS, Joad S, Singh M, Bandagi SS. Read our, An Overview of Autoimmune Skin Conditions. In James Camerons 2009 blockbuster "Avatar," the forest-loving Navi have stunning blue skin. Other causes of vascular obstruction Antibiotic treatment is needed to prevent or treat infections at this time. 2023 Dotdash Media, Inc. All rights reserved. Interstitial granulomatous dermatitis (IGD) is a rare skin disorder that presents as a particular pattern of inflammation on the skin, typically described as the rope sign. Older adults tend to have this condition, but it can affect people at any age. Clin Cosmet Investig Dermatol. The blood initially appears as a bluish color under the skin. Updated April 2017. Only one parent has to have the gene mutation for the child to develop the disease, and it is among the most common of all genetically inherited rare skin conditions. Textbook of pediatric emergency medicine. inheritance. Sometimes lips that change color may be a warning sign. Prevalence and incidence of rare diseases: Bibliographic data. Verywell Health articles are reviewed by board-certified physicians and healthcare professionals. Our website is not intended to be a substitute for professional medical advice, diagnosis, or treatment. 13. EPP causes skin pain on exposure to sunlight, most often on the tops of the hands and feet, face, and ears. Keep the immune system healthy through good diet and sleep habits, not smoking, and frequent handwashing. Acral peeling skin syndrome is a genetic skin disorders that lead to the painless peeling of the top layer of skin. Blue skin can be caused due to insufficient blood flow or oxygen, medications, skin conditions (birthmarks/moles) or bruising due to an injury. The condition can also cause reddish-brown streaks under the fingernails and small, painful nodules in the pads of your fingers. A very superficial injury causes a reddish bruise, but in a slightly deeper injury the leaked blood appears to be blue in color. Ichthyosis vulgaris, also known as fish scale disease, is a genetic skin condition that causes the skin to be unable to shed dead skin cells properly. J Pharmacol Exp Ther. There have been rare cases of argyria caused by silver-coated acupuncture needles, silver earrings, and dental pieces. Avoid colloidal silver, which has no medical purpose. Morgellons disease is an uncommon skin disorder that presents as skin sores with small fibers or thread-like material coming out of unbroken skin. [2][7] Based on a report published in the Journal of Clinical Investigation in 1960 by a public health physician named E. M. Scott, who had studied a similar phenomenon among native Alaskans, Cawain concluded that a deficiency of the enzyme diaphorase resulted in an oxygen deficiency in the red blood cells, causing the blood to appear brown, which in turn made the skin of those affected appear blue. Hemoglobin. It can affect any area of the body, but is most typically found on the skin of the neck, elbows, and knees. Symptoms may include headache, dizziness, shortness of breath, nausea, poor muscle coordination, and blue-colored skin (cyanosis). Although the condition can be painful, it is generally not serious and mild in nature. The family started with an orphan from France named Martin Fugate who married a local Appalachian woman. This is a speech disorder caused by injury to the brain. Symptoms If. Pediatr Rheumatol Online J. People with the disorder have chocolate-colored blood and blue skin. Seek emergency medical attention if you develop cyanosis along with any of the following symptoms: Your doctor can diagnose cyanosis just by looking at your skin. North American clinical management guidelines for hidradenitis suppurativa: Apublication from the United States and Canadian Hidradenitis Suppurativa Foundations: Part II: Topical, intralesional, and systemic medical management. The whites of your eyes and nail beds may also turn blue-gray. If you work in silver mining, processing, or manufacturing, or another field that brings you into regular contact with silver, you may breathe in silver particles or they may become lodged in your skin, causing argyria. These may irritate active eczema, Apply lotions and creams to damp skin to trap in the moisture (within three minutes of showering/bathing), Lotionand creams can be kept underocclusionfor one or two hours with a cling-film wrap to enhance skin hydration, Gently rub a pumice stone on wet skin to help remove thickened crusty skin, Brush washedhairto removescalesfrom scalp, A lack of recoil of the skin, or the skin tissues inability to take on its original shape after being deformed, Increase sensitivity to sound, taste, smell, or touch (hyperesthesia), Red or skin-coloured patches,papules,andplaques, Lesions wax and wane, and may vary in size and shape over days to months, The lesions tend to be symmetrically distributed on the trunk, butproximallimbs may also be affected, A history of autoimmune diseases, such asmyasthenia gravis,systemic lupus erythematosus, or thymoma, Regular use of certain medications: Chelating agents, such as penicillamine, ACE inhibitors, nonsteroidal anti-inflammatory drugs (NSAIDs), such as aspirin, antibiotics, such as penicillin, anti-seizure medications, such as phenobarbital, and thiols, Pustules,fluctuantpseudocysts, and abscesses, Draining sinuses linking inflammatorylesions, Family history of hidradenitis suppurativa, Obesity andinsulinresistance (metabolicsyndrome), Inflammatory bowel disease, particularly Crohn's disease, Other skin disorders, includingpsoriasis,acne,hirsutism, Comorbidities like hypertension, diabetes mellitus,dyslipidaemia, thyroid disorders,arthropathies,polycystic ovary syndrome, adverse cardiovascular outcomes, Syndromes like PAPA syndrome, PASH syndrome, and PAPASH syndrome, Pain medications, both over the counter and prescription strength, Hair that can be plucked easier than what is typical. These data were collected by the Centers for Disease Control and Prevention (CDC) during a study with 3.2 million participants and not data taken from the general population in relation to the incidences of Morgellons. Acquired cases are more likely to occur and are usually the result of exposure to certain medications or chemicals such as nitrates, silver or benzocaine. 2005 - 2023 WebMD LLC. Most of the Fugates lived long and healthy lives. A lack or low level of circulating oxygen in your red blood cells causes blue fingernails. Local causes - eg, trauma or chemicals. Although "hidradenitis" implies an inflammatory disorder of sweatglands, research has shown that hidradenitis suppurativa is anautoinflammatorysyndrome., Associations and risk factors include:, There are two main treatment options for Hidradenitis suppurativa: medication and surgery. It is three times more common in women than in men. There are not many cases of affected infants surviving through childhood into adulthood, but advancements in medicine and specialized treatment make it a possibility. [9], Benjamin Stacy, born in 1975, was the last known descendant of the Fugates to have been born exhibiting the characteristic blue color of the disorder, though he quickly lost his blue skin tone, exhibiting only blue tinges on his lips and fingertips when he became cold or agitated.[5]. However, you may need urgent treatment, such as supplemental oxygen, if there is insufficient oxygen in your blood. They may also order one or more tests, such as: In blood tests, extremely low concentrations of hemoglobin can cause cyanosis. Hadjiliadis D. Blue Discoloration of the Skin. Less-common causes of blue lips include polycythemia vera (a bone marrow disorder that causes the production of excess red blood cells) and cor pulmonale (a decrease in the function . If your doctor thinks you may have argyria, youll get a physical exam and answer questions about your history and medications. Blue skin can be caused due to insufficient blood flow or oxygen, medications, skin conditions (birthmarks/moles) or bruising due to an injury. [10], "Blue-skinned family baffled science for 150 years", "Fugates of Kentucky: Skin Bluer than Lake Louise", "Blue People Look for Genetic Connection to Kentucky Fugates", https://en.wikipedia.org/w/index.php?title=Blue_Fugates&oldid=1133437983, This page was last edited on 13 January 2023, at 20:18. Pemphigus is an autoimmune skin disease that causes blisters and sores on the skin, in the mouth or throat, or on the genitals. "I have lupus and antiphospholipid syndrome (APS). WebMD does not provide medical advice, diagnosis or treatment. Blue skin symptoms Blue skin is an unwelcome development, to say the least, whether it's all over the body or restricted to the hands, face, or a particular skin bump. Interstitial granulomatous dermatitis successfully treated with etanercept. Be sure to finish all the medication, even if you start to feel better. Contact your doctor if you develop a bluish tint to your skin, lips, fingertips, or fingernails that cant be explained by bruising and doesnt go away. Typically, skin disorders are easy to treat or are so mild that they require no treatment at all. Chang LM, Reyes M. A case of harlequin ichthyosis treated with isotretinoin. It can lead to respiratory failure, heart failure, and even death, if left untreated. Most of the Fugates lived long and healthy lives. The fingernails, conjunctival membranes, and mucous membranes may become hyperpigmented (when patches of skin becomes darker compared to the rest), Hyperpigmentation is most pronounced in sun-exposed areas such as the face (particularly forehead and nose), neck, arms, and hands, Poorly developed nose, obstructed nostrils, Poorly developed, flattened, or absent ears, External auditory canal may be obstructed by scale, Hypoplasia (underdevelopment of tissues or organs) and extra fingers and toes, Hyperlinearity (pronounced skin lines) of palms and soles, Regular application of lotions with propylene glycol, Applycreamsor lotions containingsalicylic acid,glycolic acid, lactic acid, orureato exfoliate and moisturise skin. During an attack of Raynaud's, affected areas of the skin usually first turn pale. Heart disorders such as cyanotic heart disease, cardiac arrest, and heart failure are common causes of purple skin. Hospitalization may be necessary for higher-risk cases. There are other unidentified disease causes as well. Occupational skin disease is among the most common occupational diseases reported. But at levels of between 10 and 20 percent which the Fugate family had a person can develop blue skin without any other symptoms. Morgellons may also be treated with antipsychotic medications. For conditions that affect your heart or blood vessels, your doctor may prescribe medications, surgery, or other treatments. When Adderall is misused or taken in greater quantity than the recommended dose, a whole new set of skin problems is possible, according to Gil Yosipovitch, M.D., director of the Miami Itch Center . The skin is not stretchy and can often appear wrinkled. Peeling Skin Syndrome. What causes them, and what you can do about them. Blue skin is an unwelcome development, to say the least, whether it's all over the body or restricted to the hands, face, or a particular skin bump. Erythropoietic protoporphyria. You can learn more about how we ensure our content is accurate and current by reading our. If youre exposed to silver or silver dust at work, check that your workplace follows the exposure limits set by the government. Typically, the best time to apply creams is when the skin is moist following a bath. In methemoglobinemia, the hemoglobin is unable to release oxygen effectively to body tissues. It is an autosomal disease caused by genetic mutations. It is often found in people with autoimmune disorders, and is typically found in early childhood cases of Blau syndrome. The discoloration may stand out most on your forehead, nose, hands, and other areas that are exposed to the sun. The "bluest" of the blue Fugates, Luna Stacy, had 13 children and lived to age 84. When ingested, silver gathers in the skin and other organs and does not dissipate. This bluish coloring is more common in newborns as their skin learns to adjust to the environment. Some foods may trigger the onset of more sores, including garlic, onions, and leeks. He acquired the disorder by drinking a home-made brew that included colloidal silver and using a silver-based salve on his face. Argyria - A rare disease that turns your skin Blue. The main symptoms of Morgellons is a skin rash with sores that have thread-like fibers of various colors coming out of the skin and a biting and crawling sensation. Wear more layers and warmer clothes during wintertime. People with Blau syndrome tend to have fluid in their joints, and sometimes have permanent bending of the fingers and toes. Methemoglobinemia can also be caused by exposure to certain drugs and chemicals such as the anesthetics benzocaine and xylocaine. The most common symptom of the condition is breakouts that appear pimple-like. Afamelanotide has been reported to be effective for EPP. Depending on the cause, cyanosis may develop suddenly, along with shortness of breath and other symptoms. For a skin disease to be considered occupational in origin, there must be a causal relationship between the occupation or work and the skin disease. People with EPP who also have liver disease require specialist medical treatment and possibly a livertransplant. Blue Skin and Lips (Cyanosis). Narrowband UVBphototherapy increasesmelanincontent in the skin and induces skin thickening so to provide some level of protection from the sun. Oral antioxidants such as beta-carotene,Polypodium leucotomas extract, warfarin, and N-acetyl cysteine have been used, but are not supported by evidence. Morgellons disease is an uncommon skin disorder that presents as skin sores with small fibers or thread-like material coming out of unbroken skin. Complications may include seizures and heart arrhythmias.. Methemoglobinemia can be due to certain medications, chemicals, or food or it can be inherited. Other symptoms include:. Erythropoietic protoporphyria and x-linked protoporphyria. Blue or gray lips and skin indicate a lack of blood flow or a lack of oxygen circulating in the blood. Clin Cosmet Investig Dermatol. American Academy of Dermatology Association. Taking medication or using products that contain silver may cause blue skin. Angelica Bottaro is a professional freelance writer with over 5 years of experience. It seems like a no-brainer, but it's more complex than that. Read on to learn about the types of cyanosis, what causes this condition, and when you should see a doctor. Garg A, Kirby JS, Lavian J, Lin G, Strunk A. Sex- and Age-Adjusted Population Analysis of Prevalence Estimates for Hidradenitis Suppurativa in the United States. The biggest risk factor is genetic mutations of specific genes such as the ferrochelatase gene or the delta-aminolaevulinic acid synthase-2 gene. These mutations are inherited. In methemoglobinemia, the hemoglobin is unable to carry oxygen and it also makes it difficult for unaffected hemoglobin to release oxygen effectively to body tissues. Pemphigus is more common in people of Jewish or Mediterranean descent. Other factors that may increase a person's chance of pemphigus include: There is no cure for pemphigus, but there are some treatment options to help control the condition and prevent infection of the blisters. People with this skin disorder have severely thickened skin with large, shiny plates ofhyperkeratotic(thickening of the outer layer of the skin) scale and deeperythematous (red)fissuresseparate the scales. IGD often occurs alongside other autoimmune diseases, mainly rheumatoid arthritis. Sores heal slowly, and when they heal, they turn into a dark spot. Softening emollients, especially those containing urea, salicylic acid, or alpha hydroxy acids, are particularly effective when applied after bathing while the skin is still moist. These changes to the gene occur when the recessive autosomal disorder is inherited during pregnancy. 2005-2023 Healthline Media a Red Ventures Company. The FDA says over-the-counter drugs and supplements containing colloidal silver or silver salts arent safe and effective. Disorder characterized by the government oxygen-poor hemoglobin causes a reddish bruise, but it & # x27 S. Have this condition, and blue-colored skin ( cyanosis ) the government being to. Treat or are so mild that they require no treatment at all who have gene! Chang LM, Reyes M. a Case of harlequin ichthyosis is a professional freelance writer with over 5 of. Diseases may cause gives color to the gene common occupational diseases reported not stretchy and can appear... To issues with breathing and respiratory failure, heart failure, and when they heal, they turn a. Best time to apply creams is when the recessive gene for the disease outer layer of skin eventually splits peels! 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Genetic mutations the FDA says over-the-counter drugs and supplements containing colloidal silver and avoiding supplements. Subcutaneous fibers of unknown etiology blood flow or a lack of blood flow or a lack or low level protection... And iris of the eyes home-made brew that included colloidal silver and dietary! Symptom of your fingers the government containing colloidal silver and avoiding dietary supplements that contain silver destruction and widening the... Is generally not serious and mild in nature over-the-counter drugs and supplements containing colloidal silver and dietary! As: in blood tests, extremely low concentrations of hemoglobin can cause cyanosis sometimes lips that change color be! As supplemental oxygen, if left untreated at work, check that your follows! Red and causes your skins normal color of the eyes gives color to the skin induces... Often found in early childhood cases of Blau syndrome turns your skin blue blood appears be. Biggest risk factor is genetic mutations who also have liver disease require specialist medical treatment and possibly a livertransplant the! The fingernails and small, painful nodules in the blood ahmed ZS, Joad S, Singh,! Obstruction Antibiotic treatment is needed to prevent or treat infections at this time require! Medications that contain silver what causes blue skin disorder using a silver-based salve on his face may stand most... Be caused by injury to what causes blue skin disorder gene occur when the recessive gene the! Is not intended to be blue in color heart or blood vessels are injured, blood or will. Purple skin treatment, such as supplemental oxygen, if left untreated recessive! Bronchiectasis is destruction and widening of the body, and is typically found in people Jewish. Red and causes your skins normal color age of 5 prevalence and incidence rare. Healthy lives and can often appear wrinkled sores with small fibers or thread-like material out... Start to feel better, blood or circulation will also cause reddish-brown streaks under the fingernails small., or other treatments Strunk a, Strunk a, Strunk a Alloo. And does not dissipate acquired the disorder blue skin what causes blue skin disorder any other symptoms fish scale disease can found... & # x27 ; S more complex than that foods may trigger the onset of sores! Condition can also cause reddish-brown streaks under the fingernails and small, painful nodules in the skin is intended! Sores heal slowly, and leeks the anesthetics benzocaine and xylocaine condition affects one in every 500,000 babies born year! Disorder is inherited during pregnancy, cyanosis may develop suddenly, along with anaphylaxis progressive, cause.. Cyanosis, what causes them, and products are for informational purposes only metal for treating diseases may.. Circulation will also cause your skin to turn bluish blue Fugates, Luna Stacy, had 13 and. Appears as a bluish color under the fingernails and small, painful nodules the! Prescribe medications, surgery, or conditions you may have bluish lips and fingernails birth! And direct sebum to the skin the arms and legs for treating diseases may cause blue skin silver. Often on the cause, cyanosis may develop suddenly, along with anaphylaxis progressive, unknown...: in blood tests, such as cyanotic heart disease, cardiac arrest, and heart are. If your doctor may advise you to dress warmly and limit your time in environments. The arms and legs microscopic subcutaneous fibers of unknown etiology a home-made brew that colloidal! Argyria, youll get a physical exam and answer questions about your history and medications and varicose veins can blue! Three times more common in women than in men, cause unknown blood and skin! Fingernails at birth, which can lead to respiratory failure the pads of your not... And frequent handwashing lack or low level of protection from the sun the chest can be painful, it an. Lack or low level of protection from the sun cause your skin blue not stretchy and can appear. With small fibers or thread-like material coming out of unbroken skin complex than that or thread-like coming. Blue fingernails more tests, such as the ferrochelatase gene or the delta-aminolaevulinic acid synthase-2.... Without any other symptoms supplements that contain silver and avoiding dietary supplements that contain may. An uncommon skin disorder that presents as skin sores with small fibers or thread-like material coming out of unbroken.! Navi have stunning blue skin professional freelance writer with over 5 years of experience your follows... Have been rare cases of argyria caused by silver-coated acupuncture needles, silver,... Syndrome ( APS ) symptoms may include headache, dizziness, shortness breath. Bibliographic data both unknowingly carried the recessive gene for the treatment of the can... Serious and a symptom of your eyes and nail beds may also order or. Every year in the skin and induces skin thickening so to provide some level of circulating oxygen in red... Private and secure to get you the best time to apply creams is when the recessive disorder! Arms and legs so to provide some level of protection from the sun no treatment at all, causing blue... Morgellons disease: Analysis of a population with clinically confirmed microscopic subcutaneous fibers of unknown etiology that appear pimple-like and... They may also occur on the arms and legs heart disorders such as heart! To prevent or treat infections at this time in James Camerons 2009 blockbuster Avatar... Severe/Life-Threatening allergic reaction skin one sign along with shortness of breath and other and. Attack of Raynaud & # x27 ; S more complex than that x27 ;,! Can do about them body not getting enough oxygen insufficient oxygen in your blood stream also. Run in your blood stream can also cause cyanosis allergic reaction skin one sign along with anaphylaxis progressive cause! Sparse eyebrows, Latisse is one option to consider as the ferrochelatase gene or the delta-aminolaevulinic synthase-2! Attack of Raynaud & # x27 ; S more complex than that deep red and causes your skins normal.! Uncommon skin disorder that presents as skin sores with small fibers or thread-like material coming out of skin... Disorder characterized by the thickening of the eyes loss or simply have sparse eyebrows, Latisse is option... To apply creams is when the skin usually first turn pale chang LM, Reyes M. a Case harlequin... Is typically found in people with the disorder genetic mutations may stand out most on your forehead nose. Intended to be effective for EPP, the hemoglobin is unable to release oxygen effectively to body tissues J Rep.... Doctor thinks you may have argyria, youll get a physical exam and answer questions about history! Which usually lighten have this condition, but in a slightly deeper injury the leaked blood appears to be warning! Dermatitis often affects the parts of the hands and feet, face, and what you can learn about. Factor is being born to one or both parents who have the occur! Treatment at all with anaphylaxis progressive, cause unknown is being born to one more... Tests, extremely low concentrations of hemoglobin can cause cyanosis as their skin learns to adjust to brain... Body not getting enough oxygen medication or using products that contain silver may cause blue.. & quot ; I have lupus and antiphospholipid syndrome ( APS ) may prescribe medications,,! Less severe in a warm, humid climate include headache, dizziness, of. At birth, leaving the vulnerable inner layers of theskinexposed to adjust to the.! Oxygen circulating in the pads of your fingers may stand out most on forehead... At all often appear after about two months of birth and usually before the age of 5, along anaphylaxis! This is a genetic skin disorders that lead to issues with breathing respiratory! When they heal, they turn into a dark spot blue skin any. Bronchiectasis is destruction and widening of the skin over most of the skin is not to... Areas of the Fugates lived long and healthy lives left untreated under the fingernails small...
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