Bifidobacterium lactis Bl-04 is a strain of bacteria found in food supplements, typically as part of a combination of strains, commercially known as HOWARU Restore. Via blood serum and saliva testing, significant changes in immunoglobulin serum concentrations were found in 6 out of the 7 probiotic supplementation groups, whereas no changes were observed in the control group. Stay up to date on upcoming products and offers. We use cookies to ensure that we can give you the very best experience. Doubts as to whether its safe for human consumption have already been addressed by several previous studies. Additionally, this probiotic combination maintained Bifidobacteria levels at significantly higher levels than that of the placebo group, even two weeks after antibiotic treatment was ceased (Engelbreksten et al. Human volunteers were orally vaccinated against cholera, and then given either a placebo or one of seven different probiotic strains including B. lactis BL-04 for a period of 21 days. ‘A randomized, double blind, controlled trial of probiotics to minimize the disruption of fecal microbiota in healthy subjects undergoing antibiotic therapy’. Because of this, it’s generally regarded to be safe for consumption. The American Journal of Clinical Nutrition, 36(6):1106-11. For further reading you can also visit the Probiotics Learning Lab, which is open to members of the public and can be signposted to clients seeking more information. They have also shown lesser incidence of nasal congestion and discharge. But for safety purposes, you should always consult with your doctor before taking any probiotic supplement. Some of them were also given seven different probiotic strains including Bl-04 for 21 days. West NP et al., (2014), ‘Probiotic supplementation for respiratory and gastrointestinal illness symptoms in healthy, physically active individuals’, Clinical Nutrition, 33(4):581-7. It can also be. This is after they detected no acquired antibiotic resistance in the strain. ‘Microbiological effects of consuming a symbiotic containing Bifidobacterium bifidum, bifidobacterium lactis, and oligofructose in elderly persons, determined by real-time polymerise chain reaction and counting of viable bacteria’. The purpose of the current study was to evaluate the effect of orally administering the probiotic Nestlé culture collection (NCC)2818 Bifidobacterium lactis strain … 2008). 110: 316-324. Lammers, K.M., et al., (2003). Randomly selected children with confirmed birch pollen allergy were given a probiotic combination of L. acidophilus and Bifidobacterium lactis Bl-04. Bifidobacterium is een geslacht van grampositieve, strikt anaerobe, niet-sporenvormende, onbeweeglijke en staafvormige bacteriën.Ze zijn in staat om glucose tot melkzuur en azijnzuur af te breken en halen hieruit hun energie. Food chem toxicol. To address this, scientists are looking into the potential of probiotics. In a randomised, double blind, placebo-controlled study, 115 participants were administered with ‘rhinovirus’ i.e. higher incidence of infections and constipation (Bartosch, 2005). Morovic, W. et al (2017) Safety evaluation of HOWARU® Restore (Lactobacillus acidophilus NCFM, Lactobacillus paracasei Lpc-37, Bifidobacterium animalis subsp. given the cold virus. lactis Bl-04 and B. lactis Bi-07) for antibiotic resistance, genomic risk factors, and acute toxicity. Now, think of probiotics as your body’s soldiers. Forssten, S. & A. Owehand. This is where probiotics enter the picture. One of the active ingredients in Bionaze™. The aim of the study was to determine whether probiotics would help to support immune function in these subjects, as significant exercise can put a strain on the immune system causing an increased risk of colds and respiratory infections. In a randomised, double blind, controlled human trial B. lactis Bl-04 was a component in a five-strain formulation investigated for its ability to support the balance of intestinal bacteria during and after antibiotic therapy. The results showed that this probiotic formulation significantly increased the levels of Bifidobacteria in the intestinal flora of the subjects.This modification of the intestinal Bifidobacteria population shows that the formulation may benefit those who have lower Bifidobacterium levels or signs of dysbiosis, e.g. Cox, AJ. Journal of Medical Microbiology, 58:663–670. Growing evidence shows that our bodies resident microbiome interacts with our immune system and may even influence immune responses; and Bifidobacteria strains, specifically BL-04™ appear to be one of the best probiotics for this purpose. Judy Ponio is a firm believer in the health benefits of probiotics and she wants to share that with the world. A total of 510 volunteers were enrolled in a study to look at the dose dependency of the effect of probiotics on diarrhoea caused by antibiotics, or diarrhoea caused by C. difficile infection. As some properties & benefits of probiotics may be strain-specific, this database provides even more detailed information at strain level. BL-04 is mostly found in the large intestines of mammals including humans. Microbial Ecology in Health and Disease, 28(1): 1378061, DOI: 10.1080/16512235.2017.1378061. No harmful side effects have also been scientifically proven to be associated with Bl-04. The primary active ingredient in Bionaze probiotic. Further inspection also showed that there is a lesser incidence of eosinophil infiltration. Randomly selected children with confirmed birch pollen allergy were given a probiotic combination of L. acidophilus and Bifidobacterium lactis Bl-04. Read more about the strains that we have included from this genus below. Some rights reserved. Among the thousands of probiotic strains, studies show that Bifidobacterium lactis Bl-04 is the best for this purpose. the replication / spread of the virus, in the probiotic group compared to placebo (Turner et al, 2017). It is commonly added to fermented dairy products such as cheese and yogurt. One probiotic supplement containing the Bl-04 strain is Bionaze. A randomized trial found that the probiotic strain B. lactis Bl-04 is especially effective in reducing the side effects of antibiotics. Foligne, B., et al., (2007). We all know that antibiotics kill disease-causing bacteria. Results indicated that their eosinophils in the nose area are reduced. It does this by regulating our body’s reactions to disease-causing microorganisms. This site includes new research and news related to probiotics. lactis were used for more detail analyses.The strains were clustered according their fingerprinting profiles. These results suggest that some probiotic strains can enhance our body’s tolerance for vaccines. © Wren Laboratories 2020. This oral probiotic comes in a lozenge form to further enhance its effectivity. 2008). Mounting evidence suggests that our resident microbiome may interact with our immune system, and may even influence immune responses; further research still needs to be done to fully establish their potential benefits, but Bifidobacteria strains appear to be one of the best probiotics for this purpose. lactis are extensively exploited by the food industry as health-promoting bacteria, although the genetic variability of members belonging to this taxon has so far not received much scientific attention. The noticeable lack of eosinophils shows reduced allergy symptoms in the study subjects. If you don’t trim the weeds regularly, time will come that it will choke out the plants and kill them. It also brings them in close contact with the intestinal immune cells. World Journal of Gastroenterology. Accept essential and anonymous cookies only. By continuing you agree to the use of cookies. Some of them were also given seven different probiotic strains including Bl-04 for 21 days. Experts are generally interested in its potential for improving gastrointestinal function, immunity and enhancing the side effects of antibiotics. This is the last thing you’d want to happen as this can weaken your immune system and cause various types of diseases. Our dog isolates showed slightly different fingerprinting profiles obtained by RAPD-PCR and REP-PCR from those isolated from yogurt and type strains of B. animalis ssp. A human study evaluated the ability of B. lactis BI-04 to encourage a healthy immune reaction in response to a vaccination. In this article, we describe the complete genetic makeup of the B. animalis subsp. Presently, both are considered B. animalis with the subspecies Bifidobacterium animalis subsp animalis and Bifidobacterium animalis subsp lactis. This study is the first describing B. animalis ssp. A recent study has proven its effect on people who are infected with the “rhinovirus” more commonly known as the cold virus. in some commercial fermented milk brands. It was found that the higher dose of probiotic gave the best results for the symptoms and frequency of diarrhoea, as well as for fever, pain and bloating, compared to the lower dose of probiotic or the placebo. Our product is formulated to be gluten free. Children with hay fever caused by a birch tree pollen were administered with a dose of BL-04 and Lactobacillus Acidophilus. Paineau, D. et al, (2008), ‘Effects of seven potential probiotic strains on specific immune responses in healthy adults: a double-blind, randomised, controlled trial’.
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